Ubiquinol CoQ10 Dosage

Q: Is the ubiquinol CoQ10 dosage different than regular CoQ10?

A: Well, here’s the difference between ubiquinol and ubiquinone:

Ubiquinone CoQ10: This is what you would call the “regular” form. It is the most widely used type in supplements.

Ubiquinol CoQ10: This is a reduced form of CoQ10 (this reduced form is what your body converts the regular form to). Since it has already been converted, there is a wide array of research which suggests it offers better absorption. The method to create this reduced from was discovered by a Japanese scientist, Dr. Tatsumasa Mae. His company patented this discovery and only licenses ubiquinol production out to a handful of manufacturers.

How is ubiquionol CoQ10 absorbed differently?
According to the manufacturer and researchers, it reportedly offers increased absorption in two different ways.

Higher CoQ10 blood levels
150mb of ubiquinol raised blood levels to a degree that would take 1200mg of ubiquinone, according to a study published in journal Regulatory Toxicology and Pharmacology. That equals out to be eight times more effective than the regular form in that study.

Stays in the blood longer
A study with rats found that regular ubiquinone CoQ10 peaks at a much lower lover and decreases dramatically over the following eight hours. When given a ubiquinol dosage, their levels peaked at an amount over 2.5x higher and after eight full hours, levels were still high; over 2x higher than ubiquinone’s peak level.

Therefore, not only is ubiquinol CoQ10 dosage reportedly better absorbed, but the research points to it lasting a lot longer in the body.

Is ubiquinol CoQ10 worth the extra cost?
Because regular CoQ10 doesn’t stay in the blood long, one of the drawbacks is that some people take it 3 or 4x per day to maintain consistent levels. With the ubiquinol CoQ10 form, it looks as if taking it less frequent may still result in sufficient levels. When you consider that fewer milligrams are reportedly needed, ironically it means that CoQ10 ubiquinol dosages are cheaper because they give you more bang for your buck. For example, instead of taking 100mg 3x daily, I now take 50mg of ubiquinol twice daily.

How to choose a ubiquinol CoQ10 supplement?
First of all, talk to your doctor before taking CoQ10 or any other dietary supplement. Get a dosage recommendation from them.

As mentioned, Kaneka CoQ10 (ubiquinol) is licensed to different manufacturers, so there are a number of brands which offer this high absorption CoQ10. A couple of the popular ones I know of are Jarrow CoQ10 and Best CoQ10. But whatever brand you choose, just remember that the research suggests that with ubiquinol, you can go with a lower dosage since it offers higher absorption. Of course, as an alternative you can always just go with the regular CoQ10 in a higher dosage and take it 3x daily.